Affinity chromatography of human liver α-D-mannosidase
نویسندگان
چکیده
منابع مشابه
Human lysosomal α-D-mannosidase regulation in promyelocytic leukaemia cells.
Lysosomal α-D-mannosidase is an exoglycosidase involved in the ordered degradation of N-linked oligosaccharides. It is ubiquitously expressed, although the main transcript is more abundant in peripheral blood leucocytes. Here we report that α-D-mannosidase enzyme activity is very high in the promyelocytic leukaemia cell lines HL60 and NB4, as compared with other leukaemic cell lines or cells fr...
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vity than did the hepatocytes. These findings would appear to generally negate the hypothesis that cellular integrity is necessary for optimum metabolism rates. However, a number of other factors must be taken into consideration. First, the results obtained are consistent with the possibility that the non-parenchymal cells (Kupffer cells) of the liver are major contributors to the metabolism of...
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background: plasminogen is one of the compounds derived from human plasma. activation of plasminogen produces plasmin. plasmin is able to lyse fibrinogen, fibrin, and some other human plasma proteins. the aim of the present work was to study the separation of human plasminogen by affinity chromatography using gel lysine sepharose. materials and methods: normal human plasma was used as the start...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1975
ISSN: 0014-5793
DOI: 10.1016/0014-5793(75)80695-8